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Oral Pathology 360- Anniversary Event
August 27, 2022 @ 17:00 – 20:00 IST
We are celebrating our second anniversary with an amazing event, and all are invited.
It is a great day for us, and we look forward to celebrating it with you. We have an academic treat planned for you, great lectures and discussions by field experts.
And thanks to our academic partner for the event Vydehi Institute of Dental Sciences & Research Center, you will get a certificate with 3 CDE points.
All you got to do now is register and attend the session.
You can also watch the event on our channel https://youtu.be/1F6wP-Udeps
Guest lectures
Title: Omics and Systems Biology tools for Precision Oral Cancer Diagnostics
This lecture delves into the potential for routine application and practical clinical utility of novel omics and systems biology tools in resource-scarce diagnostic and clinical oral histopathology settings. Several omics technology have emerged in the past decades, and the combinatorial use of omics and other existing ancillary diagnostic tools have an immense scope to improve knowledge of pathobiology and disparities in oral head and neck cancer (OHNC), in a precise and systems-oriented manner. In some developed regions of the World, seamless integration of computational bioinformatics with high-throughput omics has contributed to improving early detection, prediction, risk-profiling, and management of OHNC, at an accuracy never previously thought possible.
Emerging diagnostic omics signatures of OHNC will be discussed under the umbrella of common omics technologies such as genomics, transcriptomics, lipidomics, microbiomics, and epigenomics. Some putative barriers to the wide application of these emerging tools in resource-scarce regions will be discussed. Finally, the way forward, potential leveraging opportunities, and research educational networking potentials in resource-scarce regions will be examined.
At the conclusion of this lecture, it is envisaged that the state-of-the-art knowledge disseminated on omics tools that are currently relevant to diagnostic oral pathology in resource-scarce regions would stimulate research interest and practice, refine skills and clinical acumen, serve as an innovative global model, and ultimately improve precision diagnostic capacity in these regions.
Prof Henry Ademola ADEOLA DDS, PhD (Med.)
Division of Dermatology, Department of Medicine, Groote Schuur Hospital and the Faculty of Health Sciences, University of Cape Town, South Africa.
Professor Adeola received his Ph.D. in cancer proteomics and genomics at the University of Cape Town (UCT) through a United Nations (UN) system- International Centre for Genetic Engineering and Biotechnology (ICGEB) fellowship.
He is highly trained in advanced molecular techniques. He started his career as a dental surgeon and became a lecturer Faculty of Dental Science, the University of Port Harcourt in Rivers State, Nigeria. During his postgraduate training in Oral and Maxillofacial Pathology/Biology at Lagos University Teaching Hospital – Nigeria, he spent a year at the Niigata University Medical and Dental Hospital in Japan as a visiting research scholar in molecular patho-epidemiology and genomics of Oral, Head, and neck cancers.
In 2016, he was appointed to the UCT Health Sciences Deanery as the Project Manager of the Cancer Research Initiative (CRI) of the Faculty of Health Sciences, UCT. He provided leadership for the Ph.D. mentorship program. In addition, Prof. Henry significantly contributed to the establishment of a state-of-the-art molecular, omics, analytical, histopathology, and tissue culture laboratory at the Division of Dermatology’s Hair and Skin Research (HSR) laboratory. His stellar contributions led to his appointment as an associate professor in 2021 at the HSR laboratory of the Division of Dermatology at UCT.
He is currently the Principal Investigator and Group Leader of the Proteomics, Pathology, and Molecular Imaging (PPMI) Group at the HSR laboratory at the University of Cape Town. He is a South African National Research Foundation (NRF)-rated scientist and recipient of the UCT Faculty of Health Sciences merit award (2020-2022). He is a Principal Investigator of several grants and fundings from local and international bodies. Finally, the caliber of his teaching, research, service leadership, educational activities, and social responsiveness has resulted in several prestigious international awards and invited lead-speaker and teaching roles such as plenary, keynote, seminars, symposia, and training both within and outside the African continent.
Title: HPV and Head and Neck Cancer: Updates in Diagnosis and Testing
Over the past 2 decades, the role of high-risk HPV (HR-HPV) in developing certain head and neck cancers has become very apparent globally. In particular, HR-HPV is associated with 80-90% of oropharyngeal carcinomas in many western countries, including the USA. It also appears to play a role in selected cancers of the sinonasal cavity. In contrast, HR-HPV-associated cancers are uncommon in the oral cavity, larynx, and salivary glands. Most often, the HPV-associated cancers are squamous cell carcinoma and its variants, but occasionally HR-HPV is associated with adenocarcinomas and neuroendocrine carcinomas. HPV-associated squamous cell carcinomas of the oropharynx have a separate clinical staging system reflecting the improved prognosis among most patients. A key role for the pathologist is the proper testing of oropharyngeal cancers for HR-HPV using immunohistochemistry for p16 and/or in situ hybridization for HR-HPV E6/E7 RNA. Specific guidelines for when and how to test cancers for HR-HPV have been developed by the College of American Pathologists (CAP) and will be discussed in this lecture.
Dr. Amir Afrogheh BChD, MSc, MChD, PhD
Head of the Department of Oral and Maxillofacial Pathology, University of the Western Cape
Principle Specialist, Oral/Head and Neck Pathologist, National Health Laboratory Service
Amir Afrogheh is the Head of the Department of Oral and Maxillofacial Pathology at the University of the Western Cape (UWC), Cape Town, South Africa, and Principle Specialist at the National Health Laboratory Service (NHLS). He is also an extraordinary lecturer at the University of Stellenbosch (US), division of Anatomical Pathology. Amir holds a fellowship from Harvard Medical School, Massachusetts General Hospital in Head and Neck Pathology.
He is an international fellow of the College of American Pathologists and a member of the Endocrine Pathology Society. He has been a regularly invited speaker at major national and international pathology meetings.
Amir is the editor of the Head and Neck Pathology Journal and has published over 40 peer-reviewed papers in reputed international journals and conferences; he has authored several chapters in pathology books. Thyroid/oral cytopathology, HPV-induced cancers of the head and neck, and molecular pathogenesis of adenoid cystic carcinoma are his main areas of research interest.
In recognition of his work, he has received numerous awards and prizes, including the International Academy of Pathology ROC Kaschula award, the best early career research award (UWC), and the US best research award. He was one of five cancer researchers nominated for the prestigious Oettlé Memorial Award of the Cancer Association of South Africa in 2019.
Aside from his more scholarly pursuits, Amir enjoys canoeing, classical music, ancient studies, and literature.
